SOUTHWEST CHICKEN ALFREDO

Introduction

If you’re craving comfort food with a bit of a zesty twist, this Southwest Chicken Alfredo will hit the spot. It’s a creamy, cheesy pasta dish with a Southwestern spin—thanks to the addition of smoky spices, fresh cilantro, and sweet corn. Plus, it’s easy to make and perfect for a busy weeknight or a weekend dinner with friends. Think of it as your classic Alfredo pasta but with layers of bold, exciting flavors.

Whenever I make this dish, it brings back memories of lazy weekends when I want something hearty and flavorful, but not too complicated. It’s also a huge hit with my family; my kids especially love the combination of creamy Alfredo and slightly spicy chicken. My husband, on the other hand, always goes for seconds—and maybe thirds! This Southwest Chicken Alfredo has definitely earned a spot on our regular dinner rotation, and I’m sure it will for you too.

Why You’ll Love This Recipe

Here’s why you’ll want to make this Southwest Chicken Alfredo your new go-to:

  • Easy to Make: Minimal prep with simple ingredients, yet packed with flavor.
  • Family-Friendly: Mild enough for the little ones but customizable with extra spice for those who like it hot.
  • Rich and Creamy: The Alfredo sauce is ultra-creamy, thanks to the blend of butter, cream, and Parmesan, but it’s elevated with the addition of southwestern spices.
  • Bursting with Flavor: From the juicy, seasoned chicken to the sweet corn and kick from the jalapeños, every bite is packed with delicious contrasts.
  • Customizable: Whether you want to add extra veggies or swap out the chicken for shrimp, this recipe is versatile enough to adapt to your preferences.

Preparation Time and Servings

  • Total Time: 35 minutes
  • Prep Time: 10 minutes
  • Cook Time: 25 minutes
  • Servings: 4 generous portions
  • Calories per serving: 550
  • Protein: 40g
  • Carbs: 45g
  • Fat: 23g

Ingredients

Here’s everything you’ll need to whip up this delicious Southwest Chicken Alfredo. The best part? Most of these are pantry staples!

  • 2 boneless, skinless chicken breasts
  • 1 tablespoon olive oil
  • 1 teaspoon chili powder
  • 1 teaspoon cumin
  • ½ teaspoon smoked paprika
  • ½ teaspoon garlic powder
  • ½ teaspoon onion powder
  • ¼ teaspoon salt
  • ¼ teaspoon black pepper
  • 12 oz fettuccine pasta
  • 2 tablespoons butter
  • 3 garlic cloves, minced
  • 1 ½ cups heavy cream
  • 1 cup freshly grated Parmesan cheese
  • 1 cup sweet corn (canned, fresh, or frozen)
  • 1 small red bell pepper, diced
  • 1 small jalapeño, finely chopped (optional, for extra heat)
  • ½ cup cilantro, chopped
  • 1 lime, cut into wedges for serving

Ingredient Notes

  • Chicken: Feel free to swap for shrimp or a vegetarian protein like black beans.
  • Spices: The combination of chili powder, cumin, and smoked paprika adds that signature Southwest flavor.
  • Parmesan: Freshly grated Parmesan is key for a rich, creamy Alfredo sauce.
  • Cilantro and Lime: These bring a fresh, tangy balance to the rich Alfredo sauce.

Step-by-Step Instructions

Let’s break down the process into simple, manageable steps. Whether you’re a beginner or a seasoned cook, you can tackle this recipe with confidence.

1st Step: Cook the Pasta

  • Bring a large pot of salted water to a boil. Add your fettuccine and cook according to package instructions until al dente (about 8-10 minutes). Drain and set aside. Remember, don’t overcook the pasta—you want it to have a little bite since it’ll cook a bit more in the sauce.

2nd Step: Season and Cook the Chicken

  • While the pasta is cooking, season the chicken breasts. In a small bowl, combine chili powder, cumin, smoked paprika, garlic powder, onion powder, salt, and pepper.
  • Rub the seasoning all over the chicken breasts.
  • Heat olive oil in a large skillet over medium heat. Add the chicken breasts and cook for about 6-7 minutes per side, or until the chicken is cooked through and no longer pink in the center (internal temperature should reach 165°F).
  • Once the chicken is done, remove it from the skillet and let it rest for 5 minutes before slicing it into strips.

Cooking Tip: Don’t worry if your chicken looks a little too dark on the outside. The spices create a beautiful crust, which locks in moisture and flavor.

3rd Step: Prepare the Alfredo Sauce

  • In the same skillet, melt 2 tablespoons of butter over medium heat. Add the minced garlic and cook for about 1 minute, until fragrant but not browned.
  • Stir in the heavy cream and bring it to a simmer, stirring occasionally. Let the cream reduce slightly for about 2-3 minutes.
  • Gradually whisk in the Parmesan cheese, continuing to stir until the cheese is fully melted and the sauce becomes smooth and creamy. Reduce the heat to low.
  • Season the sauce with a pinch of salt and black pepper to taste.

Pro Tip: If your sauce gets too thick, you can always add a splash of pasta water to thin it out to your desired consistency.

4th Step: Add the Veggies

  • Now it’s time to add some Southwest flair! Stir in the corn, diced bell pepper, and jalapeño (if you’re using it). Let everything simmer together for about 2 minutes, just until the vegetables are tender but still slightly crisp.

5th Step: Combine the Pasta and Sauce

  • Add the cooked pasta to the skillet, tossing it in the Alfredo sauce until it’s fully coated. Make sure every strand of fettuccine gets that creamy goodness!

6th Step: Add the Chicken

  • Finally, add the sliced chicken on top of the pasta, stirring gently to combine everything. Let the chicken warm up in the sauce for an extra minute or two.

7th Step: Finish with Cilantro and Lime

  • Sprinkle the chopped cilantro over the pasta and give it a good squeeze of fresh lime juice to brighten up the flavors.

How to Serve

You’re ready to serve up this delicious Southwest Chicken Alfredo! Here are a few ways to present it:

  • Plate the pasta in individual servings, topping each plate with a few extra cilantro leaves and a lime wedge on the side.
  • For a little extra flair, garnish with a sprinkle of additional Parmesan cheese or a dollop of sour cream for that creamy-meets-zesty contrast.
  • Serve with warm tortilla chips or a side of avocado slices for a complete Southwestern-inspired meal.

Additional Tips

Here are a few helpful tips to ensure your Southwest Chicken Alfredo turns out perfectly every time:

  1. Don’t Overcook the Chicken: The key to tender chicken is not to overcook it. Check the internal temperature with a meat thermometer to ensure it’s just right.
  2. Use Fresh Parmesan: Freshly grated Parmesan cheese melts better and gives a richer flavor than pre-shredded varieties.
  3. Adjust Spice Levels: You can easily adjust the heat by adding more or less jalapeño or swapping it out for a milder pepper like poblano.
  4. Add Pasta Water: If the sauce gets too thick, don’t hesitate to thin it out with a little reserved pasta water.
  5. Fresh Herbs Matter: Don’t skip the cilantro and lime—they add freshness that balances the richness of the sauce.

Recipe Variations

Here are a few ways to switch up this Southwest Chicken Alfredo:

  • Vegetarian Version: Swap the chicken for roasted veggies like zucchini, mushrooms, or bell peppers. You can also add black beans for extra protein.
  • Shrimp Alfredo: Replace the chicken with shrimp. Season them with the same Southwest spices and cook them quickly in the pan before making the Alfredo sauce.
  • Spicy Alfredo: For those who like it hot, add extra jalapeños or even a dash of hot sauce to the sauce.
  • Gluten-Free: Use gluten-free fettuccine or any other pasta alternative you love.

Freezing and Storage

Have leftovers? Here’s how to store them:

  • Refrigerator: Store leftover Southwest Chicken Alfredo in an airtight container for up to 3 days. Reheat in a skillet with a splash of water or cream to bring the sauce back to life.
  • Freezer: You can freeze this dish! Let it cool completely, then transfer to a freezer-safe container. Freeze for up to 2 months. To reheat, thaw in the fridge overnight and warm in a skillet or microwave.

Special Equipment

Here’s what you’ll need for Southwest Chicken Alfredo:

  • Large Skillet: For cooking both the chicken and the Alfredo sauce.
  • Tongs: Useful for flipping the chicken and tossing the pasta.
  • Zester: Optional, but handy for grating fresh lime zest to finish the dish.

FAQ Section

  • Can I make this dish ahead of time?
    Yes! You can cook the chicken and make the Alfredo sauce in advance. Store them separately in the fridge and combine with freshly cooked pasta when you’re ready to eat.
  • What other veggies can I add?
    Feel free to toss in any of your favorites! Sautéed onions, zucchini, or roasted tomatoes would all work well.
  • Can I use pre-cooked chicken?
    Absolutely. If you’re in a rush, you can use leftover chicken or even store-bought rotisserie chicken. Just toss it in the sauce to warm it up.
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SOUTHWEST CHICKEN ALFREDO


  • Author: Dianna
  • Total Time: 25 minutes

Ingredients

Scale

For the chicken bites:

  • 1 lb (450g) boneless, skinless chicken breasts, cut into bite-sized pieces
  • 2 tablespoons olive oil
  • 2 tablespoons cornstarch (optional, for extra crispiness)
  • Salt and pepper to taste

For the honey garlic sauce:

  • 1/4 cup honey
  • 3 tablespoons soy sauce (low sodium preferred)
  • 4 garlic cloves, minced
  • 1 tablespoon apple cider vinegar (or rice vinegar)
  • 1/2 teaspoon red pepper flakes (optional, for some heat)
  • 1 tablespoon water mixed with 1 teaspoon cornstarch (for thickening)

For garnish:

  • Sesame seeds (optional)
  • Fresh chopped parsley or green onions

Instructions

1. Prepare the Chicken

Start by cutting your chicken breasts into small, bite-sized pieces. I like to aim for pieces about 1 to 1.5 inches in size, so they cook quickly and evenly. Tip: If you want extra crispy chicken, toss the pieces in cornstarch before cooking. This step is optional, but it helps create a nice, golden crust on the chicken.

Season the chicken bites with salt and pepper, making sure each piece is evenly coated. Don’t be afraid to season generously—this is where the flavor begins!

2. Cook the Chicken

In a large skillet, heat 2 tablespoons of olive oil over medium-high heat. Once the oil is hot, add the chicken bites in a single layer. You might need to do this in batches if your skillet is small—crowding the pan can cause the chicken to steam rather than brown. Let the chicken cook undisturbed for 3-4 minutes until golden brown on one side, then flip and cook for another 3-4 minutes until fully cooked through. The chicken should be golden and crisp on the outside but juicy and tender on the inside.

Pro tip: If you want to keep the chicken moist and tender, avoid overcooking it. You’ll know it’s ready when the internal temperature reaches 165°F (74°C) and the juices run clear.

3. Make the Honey Garlic Sauce

While the chicken is cooking, it’s time to whip up the star of this dish—the honey garlic sauce. In a small bowl, whisk together the honey, soy sauce, minced garlic, apple cider vinegar, and (if you like a bit of heat) red pepper flakes.

Once the chicken is cooked through and golden brown, reduce the heat to medium and pour the sauce directly into the skillet. Stir well to coat all the chicken bites in the sauce. Let it simmer for 3-5 minutes, stirring occasionally, until the sauce starts to thicken and becomes sticky. If the sauce looks too thin, add the cornstarch-water mixture and cook for another minute until the sauce thickens up.

As the sauce reduces, it will caramelize slightly, coating the chicken in a deliciously sticky glaze. You want the chicken bites to be thoroughly coated and shiny but not drowning in sauce. Pro tip: Keep an eye on the sauce—it can go from perfect to burnt quickly due to the sugar in the honey.

4. Serve and Garnish

Once the chicken bites are perfectly glazed, remove the skillet from the heat. Sprinkle with sesame seeds for a little crunch and extra flavor, and garnish with freshly chopped parsley or green onions for a pop of color and freshness. The bright green really contrasts nicely with the rich, golden glaze of the chicken!

Nutrition

  • Serving Size: 4 servings

Conclusion

This Southwest Chicken Alfredo is more than just another pasta dish—it’s an explosion of flavors that combines the creamy goodness of traditional Alfredo with the zesty kick of Southwestern spices. Whether you’re cooking for your family, entertaining friends, or just treating yourself to a hearty dinner, this dish has you covered. With simple ingredients and easy steps, it’s bound to become one of your favorite comfort foods.

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